📄 Notable^* Recent AI/ML arXiv Papers

Computational drug discovery requires agents to compose scientific operations and adapt to changing evidence and constraints. Here we introduce DrugHarness, an evolvable agent harness coupling composable scientific execution with conditional skill induction. Its environment integrates over 80 scientific operations, biomedical resources and task-specific code, preserving associations among candidates, results and artifacts. From execution trajectories and outcome feedback, DrugHarness induces act...

While Large Language Model (LLM) agents have demonstrated remarkable capabilities across complex tasks, they predominantly operate in isolated sessions, lacking the ability to continually learn from historical interactions or adapt to user-specific environments. Existing self-evolution paradigms often indiscriminately inject raw interaction trajectories into memory or skill modules, leading to obscured behavioral patterns and compromised update controllability. Furthermore, as foundational LLM r...

Single-image refocusing changes the focal plane and depth of field of a photograph after capture. It is inherently interactive: users try many focal points and blur strengths on one image, so each edit should be fast and change only the blur. Recent generative methods, however, rerun large diffusion models for every edit. We observe that the two sub-problems differ in kind: recovering the all-in-focus image is ill-posed and needs a generative prior, whereas rendering blur is largely determined b...

GRPO assigns the same group-relative advantage to equally rewarded responses within a question, leaving their generation uncertainty unused. We introduce MGE-PO, centered on four-quadrant (4Q) advantage shaping that combines verified correctness with rollout generation entropy. Correctness determines the sign of an additional correction, while entropy controls its magnitude: lower-entropy successes receive larger bonuses and higher-entropy failures receive larger penalties. An online entropy-bas...

AI agents increasingly use files and software tools to produce professional deliverables. Such work draws on materials, decisions, and feedback accumulated across assignments. We introduce OfficeTown, a generative simulation framework for professional organizations in which tasks and their context arise from continuing organizational work. From a natural-language description of an organization's purpose and activities, OfficeTown initializes an organization whose members coordinate work, delegat...

Reinforcement learning with verifiable rewards has become a scalable post-training paradigm for large language models. However, training agents over long-horizon interactions presents two challenges: using only terminal rewards makes turn-level credit assignment sparse and high-variance, while sequential mini-batch updates on a fixed rollout batch introduce policy staleness as the current policy drifts from the behavior policy. Existing approaches obtain denser credit via learned critics, proces...

Real-world frontend development requires agents to compose reproduction, generation, modification, and repair over an evolving application state. Learning a general policy for this process requires translating heterogeneous execution feedback into task-aligned rewards and effective credit assignment across long sequences of interdependent actions. We introduce WebCoder, a general frontend development agent trained with artifact-grounded agentic reinforcement learning. Our key idea is to assess d...

Large reasoning models (LRMs) exhibit strong reasoning capabilities but remain vulnerable to unsafe outputs. While Group Relative Policy Optimization (GRPO) is widely used for safety alignment, its group-relative optimization may provide insufficient safety-directed learning signals. In this paper, we identify two failure modes: advantage collapse, where homogeneous rollout groups yield vanishing advantages, and unsafe diversification, where unsafe behaviors persist and become increasingly diver...

Computer-use agents (CUAs) are commonly evaluated against fixed task specifications, but users may omit requirements, add constraints, or require approval before consequential actions. Completing the benchmark instruction does not guarantee serving the person who asked. We introduce PersonaCUABench, which holds 74 tasks across 11 domains fixed and varies only who asks. A persona agent, playing one of 44 personas in four groups, rewrites each instruction in that user's own words and answers the C...

Long-context decoding in large language models (LLMs) is increasingly bottlenecked by the memory and computation required to attend over an ever-growing Key-Value (KV) cache at each autoregressive step. Although token-level sparse attention reduces this burden by restricting computation to a small subset of relevant past tokens, its practical gains are often offset by repeatedly recomputing layer-wise sparse indices as the context grows. A common remedy is to share sparse indices across layers b...

Long-horizon agents learn from failure, but the value of a failure record can change as execution progresses. We study when retaining, compressing, or removing the same history block improves subsequent execution relative to full-history KEEP. We introduce RECAP, a framework that combines matched context interventions, execution-relational prediction, and independent policy certification. Matched environment states and rollout seeds measure success and continuation prompt-cost differences; prefi...

World models have shown considerable promise in sequential decision-making by anticipating the consequences of actions and providing predictive foresight for policy learning. However, learning to reason about counterfactual actions remains challenging, since predictive objectives may underemphasize information critical for action evaluation, while unexecuted actions lack observed futures for direct supervision. To address these challenges, we propose the World Action Critic (WAC) Model, which pr...

Large language model (LLM) agents have shown promising potential in coding tasks, and their performance is jointly determined by the policy model and the harness that mediates their interaction with the environment. Indeed, harness and policy are mutually reinforcing and evolving only one component is suboptimal---a harness tuned for one checkpoint may not target the failure modes of an updated policy, while policy learning remains limited to the trajectories elicited by a fixed harness. In ligh...

In recent years, agentic orchestration has been widely applied to solve complex human tasks. However, existing orchestration learning still faces key challenges, including hand-designed curricula, advantage collapse when a task's rollouts all reach the same outcome, and unreliable evaluation signals that judge each skill by one noisy score. To address these challenges, we propose R$^2$Orch, a new paradigm of Recursive Self-Play Orchestration: an inner loop of self-play that improves the orchestr...

Long-term memory enables LLM agents to reuse past experiences, yet retrieving relevant memories does not necessarily provide sufficient evidence for answering a query. Essential information may remain fragmented across memory records, obscured by abstraction, or disconnected from the relations required for reasoning. We identify this relevance-sufficiency gap and propose QEMem, a framework that reformulates memory utilization as the construction of query-specific evidence sets, shifting the focu...

Predicting how the world responds to an action requires more than what can be seen: robots must account for environmental factors that are neither directly observable nor explicitly specified, from physical properties such as friction and mass to human-defined environmental rules. We introduce T2-Z for test-time optimization of environment latents, which augments a robotic world model with a learnable environment latent to condition world predictions. This compact latent captures underlying envi...

Large language models (LLMs) are expanding from assisting scientific research and engineering to autonomously developing and improving AI systems, advancing AI for AI (AI4AI) as a pathway toward recursive self-improvement (RSI). Workflow-driven machine learning engineering (MLE) systems provide a practical path toward this pursuit through complex orchestration that manages long-horizon experimentation, while recent MLE systems adopt model-directed interaction, allowing models to autonomously org...

Deep search agents solve knowledge-intensive tasks through long-horizon, multi-turn interactions, where assigning credit to individual search decisions is fundamentally difficult. Outcome-based reinforcement learning provides only a single terminal reward shared across an entire trajectory. Recent process-supervision methods aim to assign credit at finer granularity, but they typically anchor credit to either surface-level trajectory states or model-internal signals, both of which become unrelia...

Large language model (LLM)-based agents and multi-agent systems increasingly tackle complex tasks through long-horizon tool use and inter-agent collaboration. However, these systems are prone to deviating from the overall goal as execution unfolds, which wastes execution resources and leads to undesired outcomes, a failure termed goal drift. In this work, we propose a steering agent that supervises execution on the fly and steers the system back on track when drift occurs. The steering agent obs...

Reasoning over long document contexts remains a challenge for large language models (LLMs). Standard retrieval methods are inherently reactive, bottlenecking agents with complex, cross-document reasoning at inference time, while precomputed structures like knowledge graphs often fall short because they rely on rigid heuristics. Instead, can we allow agents to perform anticipatory directed curation: learning to proactively reorganize unstructured corpora prior to inference to efficiently serve di...

Real desktop automation is neither purely visual nor purely programmatic. Agents must understand user-facing interfaces while efficiently manipulating files, scripts, and system state. However, native GUI/code coordination cannot be obtained by prompt-level tool composition. In our preliminary experiments, naively adding a code tool degrades a GUI agent, revealing that GUI/code routing must be internalized through training on high-quality hybrid data. We present OS-Helix, an end-to-end trained m...

Multiple patterning lithography (MPL) has been widely used to improve lithography resolution in advanced nodes, but it faces cost limits as feature sizes shrink. Directed self-assembly (DSA) offers a cost-effective complement, extending the resolution of optical lithography to sub-10 nm and beyond. Integrating DSA into MPL (DSA-MP) further enhances the resolution of contact/via patterning. Nevertheless, growing design complexity exposes the limits of existing decomposition methods, which struggl...

We present a scalable framework for solving multi-step tasks through a decentralized market of self-interested agents. Prior theoretical work demonstrated that agents organized through sequential auctions can converge to a globally optimal policy in a Markov decision process (MDP), but relied on the restrictive assumption of the existence of perfect clones as a model of perfect competition. In reality, exact clones drive agent profit to zero, violating the natural risk-reward incentives of parti...

Language model agents increasingly automate post-training, but when given the full training stack they converge on supervised fine-tuning and spend most effort revising training data. Existing systems give the agent one kind of control, selecting rows from a fixed pool or calling a generator, whereas a human data engineer adjusts proportions, prunes, repairs, replaces and synthesizes the data. We design a data action space for these changes and ask whether an automated system can make the full r...

Conventional sleep staging provides a coarse-grained representation that obscures within-stage depth variation. We developed ECG-SDI, a single-lead electrocardiography (ECG) framework for continuous sleep-depth profiling and digital biomarker extraction. Using 12,392 overnight polysomnographic recordings, we trained and validated a two-stage deep learning model supervised by conventional sleep-stage labels. Correlations with ordered stages excluding rapid eye movement (REM) sleep were 0.828 in t...

End-to-end visual generation with pixel-space loss has recently achieved competitive performance without the need for learned image tokenizers. In this work, we study whether language-informed supervision can provide a richer training signal than pixel loss for visual generation. We introduce LILIE (pronounced "lily"), a Language-Informed and Lossless Image Encoder. LILIE is an invertible image transform trained such that a vision-language model can recover captions from noised features. The enc...

Evaluating candidate changes (hypotheses) to recommendation models requires full-scale training runs consuming thousands of GPU-hours, severely limiting the hypothesis space engineers can feasibly explore. We introduce Predictable Scaling (PS), a systematic framework that exploits empirically verified regularity conditions to predict full-scale model performance from small-scale proxies. PS constructs scaled-down variants via composable scaling functions along distinct resource axes, and project...

Looped language models reuse physical Transformer blocks across logical depth, but established architectures entangle recurrence placement, input injection, and recurrent state organization. We isolate these axes in models trained from scratch at matched parameter scale, logical depth, and token budgets, and then test whether the resulting design principles transfer to resident- and active-parameter-matched Mixture-of-Experts (MoE) models. The prelude-recurrent block-coda sandwich architecture c...

GPT-6-Astra demonstrates a level of competence in robotic manipulation and navigation that challenges the conventional paradigm of building specialized models for individual tasks and embodiments. In this report, we ask not only how capable GPT-6-Astra is, but what its capabilities imply for the field. First, we probe the limits of standalone GPT-6-Astra. We conduct a large-scale evaluation across 12 representative benchmarks spanning tabletop manipulation, humanoids, mobile platforms, and dexte...